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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VARS
All Species:
29.09
Human Site:
S866
Identified Species:
40
UniProt:
P26640
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26640
NP_006286.1
1264
140476
S866
H
G
R
K
M
S
K
S
L
G
N
V
I
D
P
Chimpanzee
Pan troglodytes
XP_001160008
1264
140384
S866
H
G
R
K
M
S
K
S
L
G
N
V
I
D
P
Rhesus Macaque
Macaca mulatta
Q5TM74
1064
118624
Q729
T
L
C
S
H
G
V
Q
G
G
D
L
C
L
S
Dog
Lupus familis
XP_538837
1256
139671
S866
H
G
R
K
M
S
K
S
L
G
N
V
I
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Q9
1263
140197
S865
H
G
R
K
M
S
K
S
L
G
N
V
I
D
P
Rat
Rattus norvegicus
Q04462
1264
140350
S866
H
G
R
K
M
S
K
S
L
G
N
V
I
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520676
985
109386
V650
I
E
D
N
P
M
V
V
P
V
C
T
R
S
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088439
1243
140617
S845
H
G
R
K
M
S
K
S
L
G
N
V
I
D
P
Zebra Danio
Brachydanio rerio
XP_682807
1111
123867
C760
Y
P
T
G
I
P
E
C
G
T
D
A
L
R
F
Tiger Blowfish
Takifugu rubipres
P49696
1217
138200
S813
H
G
R
K
M
S
K
S
L
G
N
V
I
D
P
Fruit Fly
Dros. melanogaster
NP_524838
1049
118236
L714
P
E
C
G
S
D
A
L
R
F
A
L
C
A
Y
Honey Bee
Apis mellifera
XP_395202
1043
121057
L708
P
E
C
G
T
D
A
L
R
F
A
L
C
A
Y
Nematode Worm
Caenorhab. elegans
Q9U1Q4
1050
118902
D715
S
Y
T
S
Q
G
R
D
I
N
L
D
V
L
R
Sea Urchin
Strong. purpuratus
XP_001200958
1119
126755
D776
G
I
P
E
C
G
T
D
A
L
R
F
A
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93736
1108
125908
T763
R
F
A
L
V
S
Y
T
A
Q
S
D
K
I
N
Baker's Yeast
Sacchar. cerevisiae
P07806
1104
125751
D761
G
I
P
Q
C
G
T
D
A
M
R
F
A
L
C
Red Bread Mold
Neurospora crassa
P28350
1093
123334
S758
A
M
R
F
T
L
L
S
Y
T
T
G
G
G
D
Conservation
Percent
Protein Identity:
100
99.5
43.4
92.8
N.A.
93.4
93.4
N.A.
63
N.A.
65.3
45
63.8
50.9
49.1
44.9
44.4
Protein Similarity:
100
99.8
56
95.6
N.A.
96.4
96.3
N.A.
69.8
N.A.
78
58.8
76.8
63.1
63.4
59.5
59.6
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
0
N.A.
100
0
100
0
0
0
0
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
0
N.A.
100
33.3
100
6.6
6.6
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.6
42.6
40.3
Protein Similarity:
N.A.
N.A.
N.A.
58.3
60.1
56
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
6
0
0
0
12
0
18
0
12
6
12
12
6
% A
% Cys:
0
0
18
0
12
0
0
6
0
0
6
0
18
0
6
% C
% Asp:
0
0
6
0
0
12
0
18
0
0
12
12
0
42
6
% D
% Glu:
0
18
0
6
0
0
6
0
0
0
0
0
0
0
0
% E
% Phe:
0
6
0
6
0
0
0
0
0
12
0
12
0
0
6
% F
% Gly:
12
42
0
18
0
24
0
0
12
48
0
6
6
6
0
% G
% His:
42
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
12
0
0
6
0
0
0
6
0
0
0
42
6
0
% I
% Lys:
0
0
0
42
0
0
42
0
0
0
0
0
6
0
6
% K
% Leu:
0
6
0
6
0
6
6
12
42
6
6
18
6
24
0
% L
% Met:
0
6
0
0
42
6
0
0
0
6
0
0
0
0
0
% M
% Asn:
0
0
0
6
0
0
0
0
0
6
42
0
0
0
6
% N
% Pro:
12
6
12
0
6
6
0
0
6
0
0
0
0
0
42
% P
% Gln:
0
0
0
6
6
0
0
6
0
6
0
0
0
0
0
% Q
% Arg:
6
0
48
0
0
0
6
0
12
0
12
0
6
6
6
% R
% Ser:
6
0
0
12
6
48
0
48
0
0
6
0
0
6
6
% S
% Thr:
6
0
12
0
12
0
12
6
0
12
6
6
0
0
0
% T
% Val:
0
0
0
0
6
0
12
6
0
6
0
42
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
6
0
0
0
0
6
0
6
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _